Multicenter Trial of Sentinel Node Biopsy for Breast Cancer Using Both Technetium Sulfur Colloid and Isosulfan Blue Dye

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Multicenter trial of sentinel node biopsy for breast cancer using both technetium sulfur colloid and isosulfan blue dye.

OBJECTIVE To determine the factors associated with false-negative results on sentinel node biopsy and sentinel node localization (identification rate) in patients with breast cancer enrolled in a multicenter trial using a combination technique of isosulfan blue with technetium sulfur colloid (Tc99). SUMMARY BACKGROUND DATA Sentinel node biopsy is a diagnostic test used to detect breast cancer...

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Intraoperative Injection of Technetium-99m Sulfur Colloid for Sentinel Lymph Node Biopsy in Breast Cancer Patients: A Single Institution Experience

Background. Most institutions require a patient undergoing sentinel lymph node biopsy to go through nuclear medicine prior to surgery to be injected with radioisotope. This study describes the long-term results using intraoperative injection of radioisotope. Methods. Since late 2002, all patients undergoing a sentinel lymph node biopsy at the Yale-New Haven Breast Center underwent intraoperativ...

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Sentinel Lymph Node Biopsy For Breast Cancer Using Methylene Blue

Original Article Aims & objectives :Carcinoma breast is the most common malignancy in females and is the leading cause of the death in their middle age. 1/3rd of patients present with locally advanced disease with distant metastasis at the time of their initial diagnosis. Sentinel lymph node (SLN) biopsy is a reliable and minimally invasive diagnostic method to determine the regional nodal stat...

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10 % fluorescein sodium vs 1 % isosulfan blue in breast sentinel lymph node biopsy

BACKGROUND Sentinel lymph node biopsy (SLNB) is well accepted to be a standard procedure in breast cancer surgery with clinically negative lymph nodes. Isosulfan blue is the first dye approved by the USA Food and Drug Administration for the localization of the lymphatic system. Few alternative tracers have been investigated. In this study, we aimed to compare the differences between 10 % fluore...

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Is blue dye still required during sentinel lymph node biopsy for breast cancer?

BACKGROUND In early breast cancer, the optimal technique for sentinel lymph node biopsy (SLNB) is the combined technique (radioisotope and Patent Blue V) which achieves high identification rates. Despite this, many centres have decided to stop using blue dye due to blue-dye-related complications (tattoo, anaphylaxis). We evaluated the SLNB identification rate using the combined technique with a...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 2001

ISSN: 0003-4932

DOI: 10.1097/00000658-200101000-00009